Table 1 Values of the model parameters.
hbn | Description | Value | Unit | Reference |
---|---|---|---|---|
c0,Hmax,d0,Qmax | Characteristic molecule concentration | 8.24 × 10−3 | kg/m3 | |
c 2 | Maximum growth rate for the susceptible | 3 × 10−6 | s −1 | |
c 3 | Maximum death rate for the susceptible | 6.5 × 10−2 | s −1 | |
c 4 | Maximum growth rate for the persister | 3 × 10−7 | s −1 | |
c 12 | Maximum death rate for the persister | 6 × 10−4 | s −1 | |
c 5 | Maximum EPS production rate | 3.5 × 10−3 | s −1 | |
c7,c8 | Maximum nutrient consumption or antimicrobial consumption rate | 1.0 × 10−7 | s −1 | |
c A | QS molecule production rate | 6 × 10−7 | s −1 | |
c q | Growth factor production rate | 1.0 × 10−5 | s −1 | |
r a | Decaying rate of effective antibiotics | 1.0 × 10−6 | s −1 | |
bsp,bps | Conversion rate between the persister and the susceptible | 1.5 × 10−7 | .. | |
r bs | Natural death rate of susceptible bacteria | 2.0 × 10−7 | s −1 | |
r dp | Dead bacteria recycling rate into EPS | 2.2 × 10−6 | s −1 | |
D pr | Hinson constant | 0.007 | ||
k 3 | Monod constant | 3.5 × 10−3 | kg/m3 | |
k2,k8 | Monod constant | 3.5 × 10−4 | kg/m3 | |
k 9 | Monod constant | 6.6 × 10−3 | kg/m3 | |
k 12 | Monod constant | 6.0 × 10−7 | kg/m3 | |
k Q | Monod constant | 2.5 × 10−3 | kg/m3 | |
S max | Carrying capacity for the susceptible bacteria | 0.08 | ||
P max | Carrying capacity for the persister bacteria | 0.018 | ||
E max | Carrying capacity for EPS | 0.15 |