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Figure 1

From: Elevation of serum sphingosine-1-phosphate attenuates impaired cardiac function in experimental sepsis

Figure 1

Decreased S1P serum concentrations in patients with sepsis.

(a,b) S1P serum levels were assessed by LC/MS/MS in control patients (undergoing cardiac surgery prior to operation (T1 n = 11) and early postoperative (T2 n = 11) and in patients with severe sepsis/septic shock at day 1 (D1 n = 19) and day 3 (D3 n = 17) after diagnosis. (b) Septic patients were divided in 28-d survivors (D1 n = 9; D3 n = 9) and 28-d non-survivors (D1 n = 10; D3 n = 8). Data are expressed as box and whisker min to max for n number of observations. + = mean value. *P < 0.05 sepsis vs. control T1 #P < 0.05 sepsis vs. control T2 (Kruskall-Wallis test with Dunn´s multiple comparisons test).

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