Figure 2 | Scientific Reports

Figure 2

From: Elevation of serum sphingosine-1-phosphate attenuates impaired cardiac function in experimental sepsis

Figure 2

Effect of LPS/PepG on S1P serum levels and on cardiac function in C57BL/6J wild type mice.

At 18 h after LPS/PepG or vehicle (sham) administration to 2-month-old male C57BL/6J wild type mice (a) S1P serum levels were assessed by LC/MS/MS, or (b) the percentage ejection fraction was assessed by echocardiography. The following groups were studied: sham + vehicle (n = 8); LPS/PepG + vehicle (n = 8). Data are expressed as means ± SEM, ***P = 0.005 vs. sham + vehicle, ****P = 0.0001 vs. sham + vehicle (unpaired t-test).

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