Figure 1

SM was the Yiqihuoxue formula component that most strongly inhibited the TGF-β pathway.
(A) Relative activity of SBE, measured as luciferase activity, in NIH/3T3 fibroblasts treated with different components of the Yiqihuoxue formula. (B) Relative activity of SBE in NIH/3T3 fibroblasts treated with Yiqihuoxue formula from which single components had been removed. Data is presented as mean ± SD of three samples. Significant differences (as determined using one-way ANOVA test) are indicated by asterisks: *P < 0.05; **P < 0.01. YQHX, Yiqihuoxue formula; AM, Astragalus membranaceus; SM, Salviae Miltiorrhiza; AS, Angelica sinensis; SP, Semen Persicae; T, Tuyuan; AP, Agkistrodon piscivorus; CA, Centella Asiatica; GL, Ganoderma Lucidum; HE, Herba epimedii; PP, Poria peel; RG, Radix Glycyrrhizae; CS, Caulis Spatholobi.