Figure 1: Up-regulation of miR-320a in PATU8988/5-FU cells.
From: MicroRNA-320a promotes 5-FU resistance in human pancreatic cancer cells
(A) Representative curves of growth-inhibitory effects in 5-FU resistant PATU8988/5-FU and PATU8988 cells. IC50, inhibitory concentration 50. (B) Microarray of miRNA expression profile of PATU8988/5-FU and PATU8988 cells. Each sample is biologically duplicated. (C) Up-regulated microRNAs between 5-FU resistant PATU8988/5-FU cells and its parental PATU8988 cells. All data are presented as the means ± SD. Student’s t test (two-tailed) was performed to analyze data from the experiments in triplicate. P values < 0.05 were considered significant, as indicated by the asterisks (**p < 0.01, ***p < 0.001).
