Table 2 Histopathology and immunochemistry for RVFV antigen.

From: A Recombinant Rift Valley Fever Virus Glycoprotein Subunit Vaccine Confers Full Protection against Rift Valley Fever Challenge in Sheep

Sheep ID

Group

DPC

Avg H Score

Ā 

IHC

H Other Organs

IHC+

63

Mock

4

3

Ā 

+

s, k, ln, lu

s, k, ln, lu

69

Mock

4

3

Ā 

+

s, k, ln, lu

s, k, ln, lu

65

Mock

7

2

Ā 

+

k

āˆ’

68

Mock

7

2

Ā 

+

āˆ’

āˆ’

71

Mock

7

2

Ā 

+

a

a

62

Vac

7

0

Ā 

āˆ’

I

āˆ’

66

Vac

7

0

Ā 

āˆ’

k

āˆ’

67

Vac

7

0

Ā 

āˆ’

k

āˆ’

70

Vac

7

0

Ā 

āˆ’

k

āˆ’

  1. Avg H Score is average hepatic histopathology score on a scale from 0, no lesions to 3 severe lesions. DPC is days post challenge. IHC is the Liver RVFV IHC for viral antigen result. H Other Organs is histopathology in organs other than the liver. IHC + lists organs that were positive for viral antigen. Key: + = positive for viral antigen by IHC, āˆ’ā€‰= negative for viral antigen on IHC, s = spleen, k = kidney, ln = lymph node, lu = lung, a = adrenal and i = intestine.