Table 3 ABCB11 polymorphisms in patients with and without ATDILI.
Genotype | Cases N(%) | Controls N(%) | OR (95% CI) | P value | Model | OR (95% CI) | P value |
|---|---|---|---|---|---|---|---|
rs496550 | |||||||
GG | 38(43.7) | 150(43.4) | 1 (reference) | Dom | 0.95(0.60–1.53) | 0.844 | |
AG | 38(43.7) | 151(43.6) | 0.99(0.60–1.64) | 0.965 | Rec | 0.85(0.42–1.76) | 0.668 |
AA | 11(12.6) | 45(13.0) | 0.85(0.40–1.81) | 0.673 | Add | 0.94(0.67–1.32) | 0.727 |
rs2287622 | |||||||
CC | 44(50.0) | 185(52.3) | 1 (reference) | Dom | 1.06(0.67–1.68) | 0.810 | |
CT | 37(42.0) | 146(41.2) | 1.02(0.63–1.65) | 0.925 | Rec | 1.31(0.53–3.21) | 0.557 |
TT | 7(8.0) | 23(6.5) | 1.32(0.53–3.33) | 0.553 | Add | 1.09(0.75–1.58) | 0.666 |
rs3770592 | |||||||
AA | 54(60.7) | 217(61.3) | 1 (reference) | Dom | 1.02(0.63–1.64) | 0.949 | |
AT | 32(36.0) | 121(34.2) | 1.04(0.64–1.71) | 0.862 | Rec | 0.78(0.23–2.69) | 0.692 |
TT | 3(3.3) | 16(4.5) | 0.79(0.23–2.77) | 0.714 | Add | 0.98(0.66–1.47) | 0.931 |
rs2287616 | |||||||
TT | 37(43.0) | 178(50.3) | 1 (reference) | Dom | 1.31(0.81–2.11) | 0.266 | |
CT | 38(44.2) | 152(42.9) | 1.18(0.71–1.97) | 0.532 | Rec | 1.88(0.86–4.08) | 0.112 |
CC | 11(12.8) | 24(6.8) | 2.01(0.90–4.49) | 0.090 | Add | 1.33(0.93–1.90) | 0.123 |
