Table 5 Distribution of ABCB11 rs2287616 genotype in ATDILI patients with various symptoms.
Genotype distribution | χ2 | P value | ||||
|---|---|---|---|---|---|---|
Symptoms | TT N(%) | CT N(%) | CC N(%) | |||
Fever | Yes | 2(28.6) | 4(57.1) | 1(14.3) | 1.093 | 0.579 |
No | 23(47.9) | 18(37.5) | 7(14.6) | |||
Dizziness/headache | Yes | 9(37.5) | 11(45.8) | 4(16.7) | 1.087 | 0.581 |
No | 16(51.6) | 11(35.5) | 4(12.9) | |||
Gastrointestinal disorders a | Yes | 5(26.3) | 8(42.1) | 6(31.6) | 8.162 | 0.017 |
No | 20(55.6) | 14(38.9) | 2(5.6) | |||
Nausea/ vomiting | Yes | 15(38.5) | 19(48.7) | 5(12.8) | 4.264 | 0.119 |
No | 10(62.5) | 3(18.8) | 3(18.8) | |||
Fatigue/lethargy/insomnia | Yes | 6(30.0) | 9(45.0) | 5(25.0) | 4.209 | 0.122 |
No | 19(54.3) | 13(37.1) | 3(8.6) | |||
Arthralgia | Yes | 1(10.0) | 5(50.0) | 4(40.0) | 9.130 | 0.010 |
No | 24(53.3) | 17(37.8) | 4(8.9) | |||
Pruritus | Yes | 6(31.6) | 7(36.8) | 6(31.6) | 7.092 | 0.029 |
No | 19(52.8) | 15(41.7) | 2(5.6) | |||
