Figure 2: BI-1 regulates hepatic lipid accumulation, showing lipid staining.
From: Bax Inhibitor-1 regulates hepatic lipid accumulation via ApoB secretion
(a) BI-1 WT and BI-1 KO mice (8 weeks old, n = 5) were fed with HFD for 1-week and separately, 1-week-HFD-fed BI-1 KO mice were infected with GFP control virus and BI-1-expressing virus (right). (b) BI-1 WT and BI-1 KO mice (8 weeks old, n = 5) were fed with HFD for 8-weeks and separately, 8-weeks-HFD-fed BI-1 KO mice were infected with GFP control virus and BI-1-expressing virus (right). Oil Red O staining was performed. Images of liver samples were obtained at 200× original magnification. CV; central vein, NFD; normal-fat diet, HFD; high-fat diet, WT; wild-type, KO; knock-out, GFP; green fluorescent protein.
