Table 2 Demographic and clinical characteristics comparison between RSV and Non-RSV pediatric ARI cases.

From: Association of RSV-A ON1 genotype with Increased Pediatric Acute Lower Respiratory Tract Infection in Vietnam

 

Total pediatric ARI hospitalization cases during Jan 2010–Dec 2012 (n = 1854)

RSV positive ARI group (n = 426)

Non-RSV ARI group (n = 1428)

p-value #

Total number (%)/Median (IQR )

Total number (%)/Median (IQR )

Demographic information

 Male sex (%)

254 (59.6%)

799 (56.0%)

0.179

 Median age (in month)

12 (IQR: 5–21)

17 (IQR: 9–29)

<0.001***

Age group (%)

 0–12month

218 (51.2%)

528 (37.0%)

<0.001***

 13–24month

131 (30.8%)

442 (31.0%)

 

 25–36month

52 (12.2%)

187 (13.1%)

 

 37–48month

17 (4.0%)

94 (6.6%)

 

 49–60month

2 (0.5%)

(4.3%)

 

 >60month

6 (1.4%)

116 (8.1%)

 

Socioeconomic status

 Daycare attendance (%)

137 (32.2%)

552 (38.7%)

0.015*

History

 Antibiotic used prior to hospitalization (%)

169 (39.7%)

633 (44.3%)

0.042*

 Underlying medical condition (%)

133 (31.2%)

541 (37.9%)

0.012*

Clinical information

Total number (%)/Mean (95% CI )

Total number (%)/Mean (95% CI )

 

Vital sign (s)

 Mean respiratory rate (per min)

37.2 (95% CI: 36.3–38.1)

35.7 (95% CI: 35.2–36.1)

0.003**

 Mean body temperature (C.)

37.9 (95% CI: 37.8–38.0)

37.8 (95% CI: 37.8–37.9)

0.045*

 SpO2 (≦90%)

12 (2.8%)

40 (2.8%)

0.986

Respiratory symptom and sign (s)

 Wheeze (%)

225 (52.8%)

655 (45.9%)

0.012*

 Tachypnea (%)

132 (31.0%)

301 (21.1%)

<0.001***

 Difficulty breathing (%)

51 (12.0%)

157 (11.0%)

0.575

 Crackle (%)

92 (21.6%)

233 (16.3%)

0.012*

 Cough (%)

426 (100%)

1423 (99.7%)

0.221

 Chest-wall indrawing (%)

42 (9.9%)

97 (6.8%)

0.035*

LRTI and chest X-ray result

 LRTI† (%)

92 (21.6%)

307 (21.5%)

0.966

Mild LRTI (%)

43 (10.1%)

165 (11.6%)

0.402

Severe LRTI § (%)

49 (11.5%)

142 (9.9%)

0.353

 Abnormal chest X-ray (%)

62 (14.6%)

210 (14.7%)

0.856

 Radiologically-confirmed pneumonia (%)

55 (12.9%)

182 (12.8%)

0.991

Treatment and outcome (s)

 Mean onset to hospitalization (in day)

2.4 (95% CI: 2.2–2.5)

2.4 (95% CI: 2.2–2.5)

0.831

 Mean hospitalization duration (in day)

5.2 (95% CI: 4.9–5.4)

4.9 (95% CI: 4.7–5.1)

0.132

 Antibiotic used (%)

426 (100%)

1428 (100%)

1.000

 Steroid used (%)

213 (50.0%)

694 (48.6%)

0.612

  1. #All the statistically significant p-values were indicated in bold font. As the index for the statistically significant values: * were used for p-value < 0.05, ** were for p-value < 0.01 and *** were for p-value ≦ 0.001.
  2. IQR is abbreviation for Interquartile Range (1st and 3rd), and 95% CI is abbreviation for 95% Confidence Interval.
  3. †LRTI is abbreviation for “lower respiratory tract infection” and based on the WHO definition of clinical pneumonia45.
  4. §Severe lower respiratory tract infection (LRTI) was defined as presence of either danger sign, stridor or chest-wall indrawing.
Back to article page