Figure 5

Protein expression of Bcl-2, Bax, Cleaved caspase-3, Cleaved caspase-9 and NF-κB p65 (nuclei) in ox-LDL treated cardiomyocytes by western blot analysis.
(A) Representative Western blots. (B–E)Protein expression relative to GAPDH of (B) Bcl-2/Bax ratio, (C) Cleaved caspase-3, (D) Cleaved caspase-9 and (E) NF-κB p65 (nuclei); mean ± standard deviation (n = 4 for each group). Pretreatment with TAK-242 reversed the expression of these proteins. *P < 0.05 versus the control group; #P < 0.05 versus ox-LDL-treated group. GAPDH, glyceraldehyde 3-phosphate dehydrogenase.