Table 1 Characteristics of subjects by the status of islet autoimmunity (IA) and type 1 diabetes (T1D) in The Environmental Determinants of Diabetes in the Young (TEDDY) study.
Subjects who developed IA | Subjects who did not develop IA | Subjects who developed T1D | Subjects who did not develop T1D | |
|---|---|---|---|---|
Number of subjects (n) | 413 | 5061 | 115 | 5359 |
Age at first IA, T1D or the most recent visit (months) | ||||
Median | 27.9 | 69.9 | 51.4 | 72.9 |
IQR | 15.4–47.8 | 49.7–89.5 | 29.2–67.5 | 54.7–91.1 |
Country n (%) | ||||
Finland | 125 (30.3) | 1327 (26.2) | 41 (35.7) | 1411 (26.3) |
Germany | 16 (3.9) | 235 (4.6) | 6 (5.2) | 245 (4.6) |
Sweden | 159 (38.5) | 1746 (34.5) | 39 (33.9) | 1866 (34.8) |
US | 113 (27.3) | 1753 (34.7) | 29 (25.2) | 1837 (34.3) |
High-risk HLA-DR-DQ genotype n (%) | ||||
DR3/4 | 218 (52.8) | 1986 (39.2) | 65 (56.5) | 2139 (39.9) |
DR4/4 | 78 (18.9) | 1008 (19.9) | 19 (16.5) | 1067 (19.9) |
DR4/8 | 66 (16.0) | 900 (17.8) | 16 (13.9) | 950 (17.7) |
DR3/3 | 51 (12.3) | 1167 (23.1) | 15 (13.1) | 1203 (22.5) |
Gender n (%) | ||||
Female | 170 (41.2) | 2487 (49.1) | 50 (43.5) | 2607 (48.7) |
