Table 2 Adjusted hazard ratios (HR) and p-values from the Cox proportional HR models in the analysis of time-to the development of islet autoimmunity (IA) and the analysis of time to the development of type 1 diabetes respectively.
IA | Type 1 diabetes | |||
|---|---|---|---|---|
HR (95% CI) | p | HR (95% CI) | p | |
Country (Reference = US) | ||||
Finland | 1.31 (1.01–1.69) | 0.045 | 1.61 (0.99–2.62) | 0.054 |
Germany | 1.17 (0.70–1.98) | 0.552 | 1.71 (0.71–4.13) | 0.231 |
Sweden | 1.23 (0.97–1.57) | 0.088 | 1.08 (0.66–1.75) | 0.765 |
High-risk HLA-DR-DQ genotype (Reference = DR3/3) | ||||
DR3/4 | 2.37 (1.75–3.22) | <0.001 | 2.28 (1.30–4.00) | 0.004 |
DR4/4 | 1.74 (1.22–2.47) | 0.002 | 1.38 (0.70–2.72) | 0.353 |
DR4/8 | 1.57 (1.08–2.28) | 0.018 | 1.17 (0.57–2.40) | 0.669 |
Gender (Reference = Male) | ||||
Female | 0.72 (0.59–0.87) | <0.001 | 0.80 (0.56–1.16) | 0.243 |
