Figure 3 | Scientific Reports

Figure 3

From: mTOR signalling in the nucleus accumbens shell is critical for augmented effect of TFF3 on behavioural response to cocaine

Figure 3

TFF3 administration enhanced the cocaine-induced increase in mTOR signalling pathway activity in the NAc shell.

(A) Behavioural procedure. (B) The ratios of p-mTOR/mTOR and (C) p-rpS6/rpS6 were increased in the NAc shell, but without any accompanying change in the NAc core and the “saline + saline” group was used as the control. Data are expressed as the mean ± SEM. *p < 0.05, **p < 0.01 compared with “saline + saline” group; #p < 0.05 compared with “saline + cocaine” group. n=5–7 per group.

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