Table 1 Relative levels of phosphoproteins across the cell lines in the Breast Cancer Metastasis model.

From: TRPV4 Regulates Breast Cancer Cell Extravasation, Stiffness and Actin Cortex

  1. From 149 proteins detected, the proteins were subject to a 2-tier filtering system that eventually resulted in the 49 hits shown. The first filter was a 30% cut off to eliminate false positives. 30% is the technical variation of the analytical system used. The proteins that satisfied the 30% cut off (i.e., >1.3 or <0.77) were subject to a second filter whereby only iTRAQ ratios that are statistically significant i.e., p < 0.05 are selected. All statistical significance evaluation by Mann-Whitney test and Spearman correlation test were computed using Matlab®. Note: ‘NA’: Not applicable; where p-value = 0 means p-value is extremely small.
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