Table 3 Clinical parameters in follow-up PTX patients before and after PTX.

From: Association of Increased Serum Leptin with Ameliorated Anemia and Malnutrition in Stage 5 Chronic Kidney Disease Patients after Parathyroidectomy

 

Successful PTX (n = 36)

Persistent SHPT (n = 4)

Before PTX

After PTX

P

Before PTX

After PTX

P

Weight (kg)

56.8 ± 10.3

58.4 ± 10.8

0.025

57.3 ± 9.2

56.3 ± 11.4

0.572

BMI (kg/m2)

21.5 ± 3.1

21.9 ± 3.0

0.035

19.6 ± 2.5

19.3 ± 2.5

0.559

Laboratory Values

 Hemoglobin (g/l)

96.6 ± 19.5

113.4 ± 18.7

<0.001

109.0 ± 17.2

126.0 ± 21.4

0.153

 Hematocrit (%)

30.1 ± 5.9

35.7 ± 6.0

<0.001

34.1 ± 5.0

39.2 ± 6.7

0.152

 HDL cholesterol (mmol/l)

1.0 ± 0.3

1.2 ± 0.7

0.240

1.1 ± 0.2

1.0 ± 0.1

0.769

 LDL cholesterol (mmol/l)

2.5 ± 0.6

2.7 ± 0.7

0.016

2.7 ± 0.5

2.3 ± 0.7

0.242

 TC (mmol/l)

3.9 ± 0.8

4.4 ± 1.0

0.004

4.5 ± 1.1

4.4 ± 0.3

0.842

 Triglyceride (mmol/l)

1.5 ± 0.9

1.8 ± 0.9

0.032

1.9 ± 1.3

2.1 ± 2.1

0.695

 TC/HDL cholesterol

4.0 ± 1.2

4.1 ± 1.2

0.546

4.4 ± 1.2

4.5 ± 0.6

0.861

 Albumin (g/l)

37.4 ± 3.3

43.7 ± 4.4

<0.001

37.0 ± 3.3

45.9 ± 3.8

0.014

 Calcium (mg/dl)

10.1 ± 1.2

8.4 ± 1.2

<0.001

9.5 ± 0.9

8.9 ± 1.7

0.622

 Phosphorus (mg/dl)

7.0 ± 2.2

3.6 ± 1.7

<0.001

7.0 ± 0.9

5.2 ± 1.9

0.216

 lnALP

6.2 ± 0.8

5.1 ± 0.6

<0.001

6.7 ± 0.4

6.4 ± 0.1

0.342

 lniPTH

7.6 ± 0.5

3.3 ± 1.9

<0.001

7.6 ± 0.5

6.8 ± 0.7

0.308

 lnLeptin/BMI

5.5 ± 1.3

5.9 ± 1.2

<0.001

3.8 ± 1.3

3.9 ± 0.9

0.743

  1. (a) Data were mean ± SD.
  2. (b) Test of significance by a paired samples t test.
  3. (c) P: before PTX versus after PTX.
  4. (d) PTX, parathyroidectomy; SHPT, secondary hyperparathyroidism; BMI: body mass index; HDL, high density lipoprotein; LDL, low density lipoprotein; TC, total cholesterol; iPTH, intact parathyroid hormone.
  5. (e) The data of postoperative weight and lnleptin/BMI in successful PTX group was incomplete (n = 35).