Table 2 Univariate and multivariate Cox regression analyses in the training and validation set.

From: Transcriptome sequencing uncovers a three–long noncoding RNA signature in predicting breast cancer survival

Variables

Univariate model

Multivariate model

HR

95% CI of H

P-Valuea

HR

95% CI of HR

P-Valuea

Training set (N = 532)

 Three-lncRNA risk score

2.72

1.95–3.79

3.31E-09

2.74

1.98–3.81

1.50E-09

 Age

1.03

1.10-1.05

4.83E-03

1.03

1.01–1.05

3.50E-04

Validation set (N = 532)

 Three-lncRNA risk score

2.20

1.59–3.04

2.04E-06

1.99

1.44–2.74

3.14E-05

 Age

1.03

1.01–1.05

1.10E-02

1.03

1.01–0.05

1.13E-03

Training set (N = 521)

 Three-lncRNA risk score

3.11

2.08–4.44

3.46E-10

3.1

2.17–4.43

5.91E-10

 Stage

1.87

1.34–2.60

2.00E-04

1.97

1.36–2.86

3.00E-04

Validation set (N = 525)

 Three-lncRNA risk score

2.45

1.76–3.41

2.04E-07

2.74

1.77–3.55

2.00E-07

 Stage

1.71

1.21–2.42

2.00E-04

1.79

1.24–2.58

2.00E-04

Training set (N = 517)

 Three-lncRNA risk score

2.77

1.95–3.94

1.20E-08

2.62

1.83–3.75

1.37E-07

 Subtype

0.72

0.54–0.96

2.30E-02

0.84

0.63–1.13

2.40E-02

Validation set (N = 504)

 Three-lncRNA risk score

2.18

1.47–3.22

1.06E-04

2.33

1.55–3.49

4.10E-05

 Subtype

0.98

0.72–1.34

9.12E-01

1.20

0.87–1.65

2.69E-01

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