Table 2 Mean and standard error of the calculated glycosylation traits for the time points used in the statistical analysis.

From: Longitudinal monitoring of immunoglobulin A glycosylation during pregnancy by simultaneous MALDI-FTICR-MS analysis of N- and O-glycopeptides

  

trim1 *

trim3

6wkpp

26wkpp

n

trim1 vs trim3

trim3 vs 6wkpp

trim3 vs 26wkpp

%

SE

%

SE

%

SE

%

SE

Asn 144

Sialylation

61.39

0.96

63.12

0.90

59.08

1.05

59.04

0.80

25

ns

0.0002

0.0002

Bisection

25.47

0.72

27.20

0.90

28.47

0.88

26.85

0.72

25

0.0119

ns

ns

Asn 340

Sialylation

95.18

0.17

95.35

0.16

95.40

0.19

95.22

0.26

23

ns

ns

ns

Bisection

52.24

1.12

54.67

1.07

57.98

0.99

54.88

1.24

23

0.0072

0.0020

ns

Asn340 (truncated)

Galactosylation

99.84

0.01

99.83

0.01

99.82

0.01

99.84

0.01

25

ns

ns

ns

Sialylation

89.56

0.21

89.12

0.19

89.26

0.23

89.25

0.27

25

ns

ns

ns

Fucosylation

92.94

0.34

92.26

0.36

92.90

0.35

93.38

0.26

25

0.0007

0.0014

0.0005

Bisection

51.76

1.04

53.87

1.00

58.45

1.03

55.36

0.94

25

0.0001

0.0000

ns

Triantennary

5.46

0.26

6.10

0.28

5.40

0.29

5.24

0.25

25

0.0017

0.0009

0.0080

  

#

SE

#

SE

#

SE

#

SE

    

O-glycosylation

Number of GalNAcs

4.81

0.01

4.81

0.01

4.82

0.01

4.81

0.01

27

ns

ns

ns

Number of Gal

3.96

0.02

3.98

0.02

3.99

0.01

3.99

0.01

27

0.0095

ns

ns

Number of SA

3.03

0.03

3.02

0.03

3.04

0.02

3.05

0.03

27

ns

ns

ns

SA per Gal

0.77

0.01

0.76

0.01

0.76

0.01

0.77

0.01

27

ns

ns

ns

Gal per GalNAc

0.82

0.004

0.83

0.003

0.83

0.003

0.83

0.003

27

0.0109

ns

ns

 

%

SE

%

SE

%

SE

%

SE

    

% with more GalNAc than Gal

61.36

0.94

60.27

0.86

59.99

0.76

59.81

0.79

27

ns

ns

ns

% with more SA than Gal

6.49

0.43

6.79

0.36

6.69

0.30

6.59

0.31

27

ns

ns

ns

  1. In addition the number of paired samples for the Wilcoxon signed-rank test are depicted, as well as the resulting p-values. P < 0.0167 was considered as statistically significant after Bonferroni correction.
  2. *Abbreviations: trim = trimester; wkpp = weeks postpartum; GalNAc = N-acetylgalactosamine; Gal = galactose; SA = N-acetylneuraminic acid.