Table 2 Correlation analyses of subcutaneous and visceral adipose tissue HIF3A mRNA expression with metabolic parameters, methylation levels and mRNA expression of leptin and PPARG.
HIF3AmRNA Expression in subcutaneous adipose tissue | HIF3A mRNA Expression in visceral adipose tissue | |||||
|---|---|---|---|---|---|---|
r | p-value | adj. p-value | r | p-value | adj. p-value | |
Age (years) | −0.23 | 4.61 × 10−5 | 0.032 | −0.237 | 3.08 × 10−5 | 0.076 |
BMI (kg/m2) | 0.239 | 2.86 × 10−5 | 0.017 a | 0.283 | 5.46 × 10−7 | 8.84 × 10−4a |
Body weight (kg) | 0.235 | 5.56 × 10−5 | 0.467a | 0.263 | 5.45 × 10−6 | 0.280a |
Height (m) | 0.044 | 0.458 | 0.467 | 0.001 | 0.983 | 0.538 |
Waist (cm) | 0.472 | 8.41 × 10−9 | 0.010 | 0.515 | 1.89 × 10−10 | 0.048 |
Hip (cm) | 0.387 | 2.13 × 10−5 | 0.425 | 0.442 | 6.73 × 10−7 | 0.628 |
WHR | 0.172 | 0.067 | 0.018 | 0.139 | 0.135 | 0.033 |
Visceral fat area (cm2) | 0.391 | 3.19 × 10−5 | 0.636 | 0.442 | 1.71 × 10−6 | 0.479 |
SC fat area (cm2) | 0.392 | 2.99 × 10−5 | 0.240 | 0.465 | 4.06 × 10−7 | 0.604 |
CT ratio (sc/vis) | −0.259 | 7.04 × 10−3 | 0.165 | −0.319 | 7.80 × 10−4 | 0.325 |
Body fat (%) | 0.324 | 0.017 | 0.055a | 0.442 | 8.23 × 10−4 | 0.013 a |
CRP (mg/dl) | −0.138 | 0.021 | 1.8 × 10−3 | −0.153 | 0.010 | 3.19 × 10−4 |
Leucocytes/nl | −0.127 | 0.032 | 3.05 × 10−3 | −0.133 | 0.024 | 1.13 × 10−3 |
Met Blood (%) | 0.054 | 0.720 | 0.618 | 0.023 | 0.876 | 0.772 |
Met SAT (%) | −0.054 | 0.687 | 0.482 | −0.088 | 0.498 | 0.345 |
Met VAT (%) | 0.060 | 0.648 | 0.667 | −0.045 | 0.729 | 0.757 |
Leptin mRNA sc | 0.227 | 2.82 × 10−4 | 2.37 × 10−4 | 0.216 | 5.28 × 10−4 | 1.41 × 10−3 |
Leptin mRNA vis | 0.117 | 0.063 | 0.043 | 0.195 | 2.0 × 10−3 | 2.60 × 10−3 |
PPARG mRNA sc | 0.001 | 0.977 | 0.939 | 0.002 | 0.967 | 0.878 |
PPARG mRNA vis | 0.050 | 0.253 | 0.439 | 0.111 | 0.010 | 0.023 |
