Figure 1 | Scientific Reports

Figure 1

From: IL-6 mediates differentiation disorder during spermatogenesis in obesity-associated inflammation by affecting the expression of Zfp637 through the SOCS3/STAT3 pathway

Figure 1

Spermatogenesis is dependent on regular expression of Zfp637.

(A) ICC showing that Zfp637 is highly expressed and localizes in the nucleus of GC-1 spg cells. (B) IHC, (C) qRT-PCR and (D) western blot analysis were performed to evaluate the expression of Zfp637 in mouse testis tissue. (E) Effects of OE-Zfp637 in GC-1 spg cells, Zfp637 expression knockdown by siRNA-Zfp63 and the expression of TH2B detected by qRT-PCR. (F) ICC was used to measure the expression of the specific haploid cell marker, protamine 1.

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