Figure 2 | Scientific Reports

Figure 2

From: Postnatal development of the electrophysiological properties of somatostatin interneurons in the anterior cingulate cortex of mice

Figure 2

Development of the passive membrane properties of SST interneurons in the ACC after birth.

Panel (A) indicates the voltage deflections used for measuring the passive membrane properties, including P3 (top), P15 (middle) and P21 (bottom) samples. Each trace is the average of 50 response curves. Panel (B) displays the resting membrane potential (RMP). Panel (C) displays the input resistance (Rin) of cells, ***P < 0.001. Panel (D) shows the membrane time constant (τm) and panel (E) shows the membrane capacitance (Cm). The Rin significantly decreased within the first postnatal week, while the RMP and Cm gradually matured. The τm was stable prior to P14 and matured after P15; however, the maturation was slower than that of the other properties. Empty circles represent the results of eGFP-positive neurons from 44 mice. One-way ANOVAs with Tukey’s post-hoc tests were used.

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