Figure 15 | Scientific Reports

Figure 15

From: Differential responses of Trans-Resveratrol on proliferation of neural progenitor cells and aged rat hippocampal neurogenesis

Figure 15

Resveratrol treatment induces the activation of ERK1/2 and p38 MAP kinases in fontal cortex and hippocampus regions of aged rats.

(a) Protein expression profiling of p-TrkA, p-75NTR, activated caspase-3, MAPK, p-CREB and SIRT1 were studied in fontal cortex and hippocampus regions of young rats, aged rats and Resveratrol (20 mg/kg body weight, p.o., for 45 days) treated aged rats. (b) β-actin was used as internal control to normalize the data. Quantification of proteins was done in Gel Documentation System (Alpha Innotech, USA) with the help of AlphaEaseTM FC StandAlone V.4.0 software and expressed in fold change. *p < 0.05; **p < 0.01; ***p < 0.001.

Back to article page