Figure 9

Resveratrol induced proliferation of NPCs via activation of ERK1/2 and p38 signalling molecules.
Neural progenitor cells were treated with the indicated kinase inhibitors for 1 h with subsequent treatment with 10 μM Resveratrol for 24 h and MTT assays were performed. Inhibitors used were: PD98059 (ERK inhibitor), SB203580 (p38 inhibitor), SP600125 (JNK inhibitor). Data represents mean ± SE of three independent experiments. *p < 0.05; **p < 0.01; ***p < 0.001 (Vehicle vs experimental group).