Figure 4: Phenotype-related gene expression in aortic media of BAPN-treated mice. | Scientific Reports

Figure 4: Phenotype-related gene expression in aortic media of BAPN-treated mice.

From: β-Aminopropionitrile monofumarate induces thoracic aortic dissection in C57BL/6 mice

Figure 4

C57BL/6 mice were administered vehicle or BAPN for 4 wk. (a–c) qPCR analysis of MMP2/3/9 mRNA levels; n = 8, *P < 0.05, **P < 0.01. (d–f) qPCR analysis of Cathepsin S/K/L mRNA levels (n = 8 per group); *P < 0.05, **P < 0.01. (g–j) qPCR analysis of COL1α1, α-SMA, CTGF and β-MHC mRNA levels (n = 8 per group); *P < 0.05, **P < 0.01, ***P < 0.0001.

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