Table 3 IC50 values for different formulations across different cell lines.

From: Pro-haloacetate Nanoparticles for Efficient Cancer Therapy via Pyruvate Dehydrogenase Kinase Modulation

Cancer Cells

IC50 (μM)

Pro-DCA-NP

Pro-MCA-NP

Pro-DBA-NP

DCA

MCA

DBA

Panc-1

45 ± 05

35 ± 05

60 ± 06

≫500

>500

450 ± 45

MCF-7

150 ± 15

40 ± 05

45 ± 05

≫500

140 ± 15

>500

MDA-MB231

50 ± 05

10 ± 05

30 ± 05

≫500

400 ± 50

>500

BT549

180 ± 20

100 ± 10

100 ± 10

≫500

>500

>500

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