Table 2 The starting linear mixed (multi-level) model with IgG1 galactosylation as dependent variable is shown, as well as the final model after sequential removal of total IgE level, age, sex, CRP level, and schistosomiasis status as non-significant fixed effects.
From: IgG1 Fc N-glycan galactosylation as a biomarker for immune activation
Model | Effects | Parameter | b | P value | 95% CI | |
|---|---|---|---|---|---|---|
Starting model | Fixed | Intercept | 47.64 | <0.001 | 43.44 | 51.84 |
Sex | 0.68 | 0.155 | −0.26 | 1.61 | ||
Age | −0.06 | 0.670 | −0.33 | 0.21 | ||
Log(CRP level) | −0.66 | 0.068 | −1.37 | 0.05 | ||
Log(Total IgE level) | −0.11 | 0.787 | −0.92 | 0.69 | ||
Schistosomiasis | −2.41 | 0.024 | −4.50 | −0.32 | ||
STH infection | −1.24 | 0.059 | −2.53 | 0.05 | ||
Random | Residual | 30.29 | <0.001 | 26.88 | 34.15 | |
Intercept (Community) | 5.55 | 0.052 | 2.02 | 15.21 | ||
Final model | Fixed | Intercept | 48.62 | <0.001 | 46.82 | 50.43 |
STH infection | −1.37 | 0.028 | −2.58 | −0.15 | ||
Random | Residual | 30.99 | <0.001 | 27.73 | 34.63 | |
Intercept (Community) | 8.47 | 0.019 | 3.68 | 19.51 | ||
