Table 3 Univariate and multivariate analysis of prognostic markers for overall survival in gastric cancer.

From: Prognostic value of decreased expression of RBM4 in human gastric cancer

 

Univariate analysis

Multivariate analysis

HR

P-value

95% CI

HR

P-value

95% CI

RBM4 expression

0.449

<0.001*

0.324 0.624

0.470

<0.001*

0.315 0.701

 High vs Low or no

      

Age (years)

2.012

0.005*

0.512 0.987

0.868

0.330

0.546 1.225

 ≤60 vs >60

      

Gender

1.025

0.923

0.805 1.709

   

 Male vs Female

      

Histological type

1.407

0.020*

0.762 1.095

0.851

0.489

0.538 1.346

 Tubular vs Mucinous vs Mixeda vs Signet ring cell vs Othersb

      

Differentiation

0.210

<0.001*

1.549 2.747

1.383

0.053

0.996 1.920

 Well vs Middle vs Poor

      

TNM stage

8.415

<0.001*

5.691 12.444

7.288

<0.001*

4.757 11.166

 0+I+II vs III+IV

      

Depth of invasion

5.120

<0.001*

3.576 7.332

   

 Tis vs T1+T2 vs T3+T4

      

Lymph node metastasis

2.320

<0.001*

1.968 2.735

   

 N0 vs N1 vs N2 vs N3

      

Distant metastasis

7.135

<0.001*

2.775 18.346

   

 M0 vs M1

      
  1. HR, Hazard ratio; CI, confidence interval. *P < 0.05.
  2. aMixed: Tubular and mucinous.
  3. bothers: Papillary adenocarcinoma, 6 cases; Adeno squamous carcinoma, 2 cases; Squamous cell carcinoma, 3 cases; Neuroendoccrine carcinoma, 1 case.
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