Table 2 Univariate Cox regression for DFS in the retrospective study.

From: Optimal pathological response indicated better long-term outcome among patients with stage IB2 to IIB cervical cancer submitted to neoadjuvant chemotherapy

Variables

HR

95% CI

P

Pathological response

OPR VS Non-OPR

11.05

1.54 to 79.45

0.02

Age

>44 VS ≤44 years

1.61

1.05 to 2.48

0.03

Stage

IIA VS IB2

2.18

1.13 to 4.20

0.02

 

IIB2 VS IB2

2.44

1.33 to 4.48

0.004

Tumor size

>4 cm VS ≤4 cm

1.37

0.86 to 2.19

0.19

Grade

G2 VS G1

2.16

0.67 to 7.01

0.20

 

G3 VS G1

3.38

1.06 to 10.81

0.04

 

Undetermined VS G1

2.05

0.60 to 6.97

0.25

Cell type

Squamous VS non-squamous

2.24

1.32 to 3.82

0.003

LVSI

Positive VS negative

1.40

0.75 to 2.61

0.29

Parametrial infiltration

Positive VS negative

2.61

1.53 to 4.44

<0.001

Vaginal surgical margin

Positive VS negative

1.91

0.83 to 4.41

0.13

Lymph node metastasis

Positive VS negative

3.68

2.21 to 6.12

<0.001

  1. LVSI, Lymph vascular space invasion. DFS, disease free survival.