Table 3 Univariate Cox regression for DFS in the prospective study.

From: Optimal pathological response indicated better long-term outcome among patients with stage IB2 to IIB cervical cancer submitted to neoadjuvant chemotherapy

Variables

HR

95% CI

P

Pathological response

OPR VS Non-OPR

3.65

0.89 to 14.92

0.07

Age

>44 VS ≤44 years

2.18

1.30 to 3.67

0.003

Stage

IIA VS IB2

1.61

0.64 to 4.09

0.31

 

IIB2 VS IB2

2.56

1.20 to 5.43

0.01

Tumor size

>4 cm VS ≤4 cm

0.93

0.56 to 11.57

0.23

Grade

G2 VS G1

1.30

0.39 to 4.36

0.69

 

G3 VS G1

1.94

0.58 to 6.55

0.28

 

Undetermined VS G1

2.40

0.70 to 8.20

0.16

Cell type

Squamous VS non-squamous

1.45

0.68 to 3.12

0.34

LVSI

Positive VS negative

2.48

0.92 to 6.68

0.07

Parametrial infiltration

Positive VS negative

3.32

1.20 to 9.16

0.02

Vaginal surgical margin

Positive VS negative

4.04

1.71 to 9.54

0.001

Lymph node metastasis

Positive VS negative

2.62

1.44 to 4.78

0.002

  1. LVSI, Lymph vascular space invasion; DFS, disease free survival.