Figure 1

miR-203 was downregulated in the CRC clinical specimens and the human CRC cell lines.
(A) miR-203 expression was determined by qRT-PCR in 72 pairs of CRC tissue (T) and the corresponding adjacent non-tumor tissue (N). (B) The miR-203 expression level was investigated in primary CRC tissues with metastasis or without metastasis. (C) Assessment of miR-203 levels from the total RNA derived from CRC tissues according to the tumor stage. (D) The relative expression of miR-203 in the CRC cell lines compared with the normal human intestinal epithelial cell line HIEC. *p < 0.05, **p < 0.01.