Table 2 Univariate and multivariate analyses of the association of prognosis with clinicopathologic parameters and miR-203 expression in CRC patients.
Variable | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Age (<50/≥50) | 0.741 (0.368–1.275) | 0.362 | – | – |
Gender (male/female) | 1.308 (0.694–2.147) | 0.618 | – | – |
Differentiation (well/moderately, poorly) | 1.324 (0.780–2.409) | 0.356 | – | – |
Tumor size (<5 cm/≥5 cm) | 1.182 (0.836–1.582) | 0.367 | – | – |
Tumor location (Colon/Rectum) | 0.946 (0.703–1.422) | 0.306 | – | – |
Lymph node metastasis (present/absent) | 6.545 (3.184–11.608) | <0.001 | 4.234 (3.104–8.332) | 0.03 |
TNM stage (AJCC) (I-II/III-IV) | 5.501 (2.243–13.462) | <0.001 | 5.043 (2.417–9.455) | 0.007 |
miR-203 expression (high/low) | 2.687 (1.204–5.764) | 0.003 | 1.725 (1.139–3.053) | 0.016 |
