Figure 6
In vivo photothermal imaging and photothermal ablation of HeLa tumors.
(a) Full-body photothermal images of HeLa tumor-bearing mice after IT injection with 0.1 mL PBS (control, the right mouse, indicated at region Ar2) or Fe3O4 @ Au-PEI.Ac-PEG-FA NSs dispersed in 0.1 mL PBS ([Au] = 20 mM, the left mouse, indicated at region Ar1), followed by exposure to an 808 nm laser with a power density of 1.0 W/cm2 at a time point of 0 min, 2.5 min and 5 min, respectively. (b) The plot of temperature increase in tumor regions (Ar1 and Ar2) as a function of irradiation time. (c) The tumor volume change profiles, (d) body weight change and (e) survival rate of tumor-bearing mice (n = 4) as a function of time posttreatment.
