Figure 3
From: The space of enzyme regulation in HeLa cells can be inferred from its intracellular metabolome

Global changes in enzyme activity between HeLa and HaCaT cells.
Changes in enzyme activities are shown as mean log2-fold changes between HeLa and HaCaT cells. Each point denotes a single irreversible reaction and reactions are grouped by metabolic pathway. Circles denotes the expected differential enzyme activities predicted by the transformation matrix T and triangles denote regulations that are necessary for proliferation.