Table 1 Baseline parameters of study participants according to the MetS status at follow-up.

From: The Effects of Serum ANGPTL8/betatrophin on the Risk of Developing the Metabolic Syndrome – A Prospective Study

Characteristic

Male (n = 66)

Female (n = 87)

non-MetS

MetS

p

non-MetS

MetS

p

N (%)

48 (72.7)

18 (27.3)

 

77 (88.5)

10 (11.5)

 

Age (years)

51.1 ± 7.9

50.8 ± 7.2

0.899

51.6 ± 6.0

49.3 ± 5.7

0.261

Current/former smoke n(%)

21 (43.8)

4 (22.2)

0.187

22 (28.6)

4 (40.0)

0.707

Alcohol drinking n(%)

28 (58.3)

10 (55.6)

1.000

34 (44.2)

7 (70.0)

0.229

BMI (kg/m2)

23.4 ± 2.6

26.3 ± 2.9

0.000

23.1 ± 2.5

25.0 ± 2.6

0.036

WC (cm)

83.6 ± 7.5

91.7 ± 8.9

0.000

78.4 ± 6.5

83.7 ± 9.4

0.024

WHR

0.88 ± 0.05

0.92 ± 0.06

0.004

0.84 ± 0.05

0.86 ± 0.05

0.266

SBP (mmHg)

121.9 ± 13.5

124.3 ± 11.0

0.499

116.1 ± 12.5

121.1 ± 13.1

0.239

DBP (mmHg)

78.9 ± 8.6

81.5 ± 8.7

0.285

74.5 ± 8.4

80.0 ± 7.9

0.053

FPG (mmol/L)

5.20 ± 0.46

5.39 ± 0.39

0.120

5.26 ± 0.44

5.27 ± 0.32

0.937

2hPG (mmol/L)

5.75 ± 1.61

6.78 ± 1.45

0.020

6.93 ± 1.54

6.28 ± 0.95

0.197

FINS (mIU/L)

16.79 ± 11.11

11.13 ± 5.54

0.051

17.37 ± 6.38

15.83 ± 6.66

0.493

HbA1c (%)

5.55 ± 0.33

5.51 ± 0.51

0.687

5.81 ± 0.44

5.76 ± 0.44

0.747

Triglycerides (mmol/L)

1.1 (0.8–1.5)

1.4 (1.2–2.0)

0.025

1.1 (0.8–1.5)

1.4 (1.0–1.6)

0.353

Cholesterol (mmol/L)

4.73 ± 0.89

5.22 ± 1.01

0.058

5.11 ± 1.01

5.04 ± 0.87

0.846

HDL-c (mmol/L)

1.37 ± 0.30

1.28 ± 0.30

0.306

1.63 ± 0.41

1.38 ± 0.25

0.066

LDL-c (mmol/L)

2.92 ± 0.80

3.45 ± 0.73

0.017

3.03 ± 0.81

3.27 ± 0.74

0.366

ALT (U/L)

23 ± 12

32 ± 31

0.095

17 ± 8

20 ± 16

0.546

AST(U/L)

22 ± 8

26 ± 13

0.080

20 ± 6

21 ± 8

0.669

GGT (U/L)

31 ± 18

36 ± 14

0.321

21 ± 14

25 ± 17

0.422

Log(HOMA-IR) (units)

0.52 ± 0.29

0.36 ± 0.23

0.022

0.58 ± 0.16

0.53 ± 0.22

0.419

Subcutaneous fat (cm2)

108.83 ± 45.49

144.44 ± 43.21

0.006

171.63 ± 55.64

197.01 ± 54.05

0.177

Visceral fat (cm2)

68.92 ± 40.29

113.89 ± 61.75

0.001

54.35 ± 23.46

70.35 ± 25.43

0.048

  1. BMI, body mass index; WC, waist circumference; WHR, waist-hip ratio; SBP, systolic blood pressure; DBP, diastolic blood pressure; FPG, fasting plasma glucose; 2hPG, two-hour postprandial plasma glucose; FINS, fasting insulin; HDL-c, high-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol; ALT, alanine aminotransferase; AST, aspartate transaminase; GGT, glutamyl transpeptidase.
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