Figure 6
From: A previously unrecognized role of C3a in proteinuric progressive nephropathy
C3 and C3a, CD24, CXCR4 and GDNF expression in renal biopsies of patients with focal segmental glomerulosclerosis (FSGS).
(A) Representative double immunofluorescence staining for C3 (green) and PECs labelled for CD24 (red) in normal control kidney (n = 4) and in the renal biopsy of patients with FSGS (n = 10). (B,C) Co-staining for CXCR4 (red) and C3 (green) (B) and GDNF (red) and C3 (green) (C) in normal subjects and FSGS patients. (D) Representative images of C3a immunostaining of renal tissue in normal and diseased kidneys. Data information: Podocytes and PECs are indicated with arrows and arrowheads, respectively. DAPI (blue) stains nuclei. Scale bars: 50 μm.
