Table 2 Comparison and correlation of LCI and MMEF% predicted in different subgroups.

From: Maximal mid-expiratory flow is a surrogate marker of lung clearance index for assessment of adults with bronchiectasis

Ā 

No.

LCI Median (95% CI)

MMEF predicted% Median (95% CI)

r Value of Correlation #

P Value of Correlation #

All patients

110

14.70 (14.49, 16.13)

45.30 (41.72, 52.72)

āˆ’0.64

<0.01

0ā‰¤ BSI ā‰¤4

38

12.90 (12.57, 15.05)

50.64 (46.06, 65.23)

āˆ’0.61

<0.01

5ā‰¤ BSI ā‰¤8

39

14.60 (13.68, 15.96)

47.02 (39.43, 58.72)

āˆ’0.64

<0.01

BSI ā‰„9

33

16.90 (15.89, 19.37)

22.87 (26.55, 44.09)

āˆ’0.65

<0.01

P value *

ā€“

<0.01

<0.01

ā€“

ā€“

HRCT score ā‰¤6

44

12.40 (11.84, 13.18)

66.14 (58.26, 74.01)

āˆ’0.48

<0.01

7ā‰¤ HRCT score ā‰¤12

46

16.20 (14.60, 16.69)

34.26 (32.11, 46.61)

āˆ’0.71

<0.01

HRCT score ā‰„13

20

19.15 (18.73, 22.69)

16.32 (14.78, 32.57)

āˆ’0.12

0.66

P value **

ā€“

<0.01

<0.01

ā€“

ā€“

  1. 95% CI: 95% confidence interval LCI: lung clearance index; MMEF: maximal mid-expiratory flow.
  2. *Comparison among patients with BSI less than 5, BSI of 5 or greater and 8 or lower, and those with BSI of 9 or greater.
  3. **Comparison among patients with HRCT total score less than 7, HRCT total score of 7 or greater and 12 or lower, and those with HRCT total score of 13 or greater.
  4. #Because LCI and MMEF% predicted might have been biased by age, sex and body-mass index, the correlation between LCI and MMEF% predicted in different subgroups was analyzed with partial correlation model, adjusting for the patientā€™s age, sex and body-mass index.
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