Table 3 Concordance of lung clearance index and maximal mid-expiratory flow with clinical variables in stable bronchiectasis.

From: Maximal mid-expiratory flow is a surrogate marker of lung clearance index for assessment of adults with bronchiectasis

	Lung clearance index				Maximal mid-expiratory flow
	Lower 50^th percentile ^*	Upper 50^th percentile ^*	Total	Concordance (95% CI)	Lower 50^th percentile ^**	Upper 50^th percentile ^**	Total	Concordance (95% CI)
≤3 bronchiectatic lobes	35	6	41	0.527 (0.376, 0.678)	33	8	41	0.455 (0.294, 0.616)
>3 bronchiectatic lobes	20	49	69	0.527 (0.376, 0.678)	22	47	69	0.455 (0.294, 0.616)
Total	55	55	110	–	55	55	110	–
HRCT total score ≤9	51	22	73	0.527 (0.376, 0.678)	48	25	73	0.418 (0.257, 0.579)
HRCT total score >9	4	33	37	0.527 (0.376, 0.678)	7	30	37	0.418 (0.257, 0.579)
Total	55	55	110	–	55	55	110
BSI ≤5	33	16	49	0.309 (0.133, 0.485)	32	17	50	0.273 (0.095, 0.451)
BSI >5	22	39	61	0.309 (0.133, 0.485)	23	38	60	0.273 (0.095, 0.451)
Total	55	55	110	–	55	55	110	–
Unilateral bronchiectasis	18	2	20	0.291 (0.154, 0.423)	18	2	20	0.291 (0.154, 0.423)
Bilateral bronchiectasis	37	53	90	0.291 (0.154, 0.423)	37	53	90	0.291 (0.154, 0.423)
Total	55	55	110	–	55	55	110	–
Tubular/varicose bronchiectasis	25	9	34	0.291 (0.126, 0.456)	23	11	34	0.218 (0.049, 0.387)
Cystic bronchiectasis	30	46	76	0.291 (0.126, 0.456)	32	44	76	0.218 (0.049, 0.387)
Total	55	55	110	–	55	55	110	–
Homogeneity	25	6	31	0.345 (0.186, 0.504)	23	8	31	0.273 (0.110, 0.436)
Heterogeneity	30	49	79	0.345 (0.186, 0.504)	32	47	79	0.273 (0.110, 0.436)
Total	55	55	110	–	55	55	110	–
No Pseudomonas aeruginosa colonized	45	34	79	0.200 (0.035, 0.365)	44	35	79	0.164 (−0.003, 0.331)
Pseudomonas aeruginosa colonized	10	21	31	0.200 (0.035, 0.365)	11	20	31	0.164 (−0.003, 0.331)
Total	55	55	110	–	55	55	110	–
FEV₁ predicted ≤80%	5	25	30	−0.364 (−0.519, −0.209)	29	1	30	0.509 (0.366, 0.652)
FEV₁ predicted >80%	50	30	80	−0.364 (−0.519, −0.209)	26	54	80	0.509 (0.366, 0.652)
Total	55	55	110	–	55	55	110	–

Data are presented with counts unless otherwise stated. 95% CI: 95% confidence interval LCI: lung clearance index; MMEF: maximal mid−expiratory flow.
^*For LCI, “Low” denoted the values being equal to or lower than the median (14.70), whereas “high” indicated the values being higher than the median (14.70).
^**For MMEF predicted%, “Low” denoted the values being equal to or lower than the median (45.3%), whereas “high” indicated the values being higher than the median (45.3%).

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Table 3 Concordance of lung clearance index and maximal mid-expiratory flow with clinical variables in stable bronchiectasis.

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