Table 4 Fixed-effect estimates in multivariate linear mixed model of the clinical variable attributes’ impacts on lung clearance index and maximal mid-expiratory flow.
LCI | MMEF predicted% | |||||
|---|---|---|---|---|---|---|
Estimate | P value | 95% CI | Estimate | P value | 95% CI | |
Intercept | 15.571 | <0.001 | 14.115, 17.028 | −19.434 | <0.001 | −20.890, −17.978 |
No. of bronchiectatic lobes | −0.254 | 0.046 | −0.505, −0.004 | −1.519 | <0.001 | −1.769, −1.269 |
HRCT total score * | 0.477 | <0.001 | 0.372, 0.582 | 0.521 | <0.001 | 0.416, 0.626 |
Age | 0.051 | <0.001 | 0.037, 0.066 | 0.028 | <0.001 | 0.014, 0.043 |
FEV1 predicted% | −0.080 | <0.001 | −0.091, −0.068 | 1.048 | <0.001 | 1.037, 1.060 |
Sex | – | – | – | – | – | – |
Males | Reference | Reference | Reference | Reference | Reference | Reference |
Females | 0.371 | 0.072 | −0.034, 0.776 | 1.542 | <0.001 | 1.137, 1.947 |
Sputum bacteriology | – | – | – | – | – | – |
Pseudomonas aeruginosa colonized | Reference | Reference | Reference | Reference | Reference | Reference |
No Pseudomonas aeruginosa colonized | −0.484 | 0.037 | −0.939, −0.028 | −2.576 | <0.001 | −3.032, −2.120 |
Cystic bronchiectasis | – | – | – | – | – | – |
Yes | Reference | Reference | Reference | Reference | Reference | Reference |
No | 0.748 | 0.004 | 0.245, 1.252 | −3.082 | <0.001 | −3.586, −2.578 |
Heterogeneity | – | – | – | – | – | – |
Yes | Reference | Reference | Reference | Reference | Reference | Reference |
No | −0.518 | 0.038 | −1.006, −0.029 | 1.087 | <0.001 | 0.598, 1.575 |
Bilateral bronchiectasis | – | – | – | – | – | – |
Yes | Reference | Reference | Reference | Reference | Reference | Reference |
No | −0.857 | 0.008 | −1.494, −0.219 | 3.420 | <0.001 | 2.783, 4.058 |
