Table 1 Characteristics of all Surveillance, Epidemiology and End Results(SEER) program and in-institute participants, by cancer stages.
All patient N = 45904 | Stage IA N = 12769 | Stage IB N = 6658 | Stage IIA N = 3384 | Stage IIB N = 3194 | StageIIIA N = 6911 | Stage IIIB N = 1929 | Stage IV n = 11059 | |
|---|---|---|---|---|---|---|---|---|
Age at diagnosis—median(Range) | 70(30,112) | 70(30,112) | 71(30,97) | 69(30,96) | 70(31,101) | 69(30,96) | 69(31,94) | 69(30,102) |
Age at diagnosis—mean(SD) | 68.98(10.0) | 69.08(10.0) | 70.05(10.30) | 68.79(10.43) | 69.22(10.22) | 68.74(10.41) | 68.05(10.75) | 68.52(10.98) |
Race—Number(%) | ||||||||
Caucasian | 37542(81.8) | 10634(83.3) | 5464(82.1) | 2743(81.1) | 2695(84.4) | 5568(80.6) | 1553(80.5) | 8875(80.3) |
African-American | 4745(10.3) | 1054(8.3) | 605(9.1) | 338(10.0) | 301(9.4) | 768(11.1) | 256(13.3) | 1423(12.9) |
Asian | 3627(7.9) | 1081(8.5) | 589(8.8) | 303(9.0) | 198(6.2) | 575(8.3) | 120(6.2) | 761(6.9) |
Sex—Number(%) | ||||||||
Male | 23244(50.6) | 5486(4.3) | 3282(49.3) | 1803(53.3) | 1689(52.9) | 3778(54.7) | 1099(57.0) | 6106(55.2) |
Female | 22660(49.4) | 7283(5.7) | 3376(50.7) | 1581(46.7) | 1505(47.1) | 3132(45.3) | 830(43.0) | 4953(44.8) |
Grade—Number(%) | ||||||||
Well-differentiated | 7456(16.2) | 3971(31.1) | 1165(17.5) | 371(11.0) | 525(16.4) | 539(7.8) | 97(5.0) | 788(7.1) |
Moderately-differentiated | 18792(40.9) | 5696(44.6) | 3172(47.6) | 1514(44.7) | 1312(41.1) | 2789(40.4) | 692(35.9) | 3617(32.7) |
Poorly-differentiated | 19183(41.8) | 3041(23.8) | 2270(34.1) | 1466(43.3) | 1322(41.4) | 3503(50.7) | 1118(58.0) | 6463(58.4) |
undifferentiated | 473(1.1) | 61(0.5) | 51(0.8) | 33(1.0) | 35(1.1) | 80(1.2) | 22(1.1) | 191(1.7) |
Histology | ||||||||
Squamous cell carcinoma | 15989(34.8) | 3266(25.6) | 2309(34.7) | 1413(41.8) | 1358(42.5) | 3023(43.7) | 1011(52.4) | 3608(32.6) |
Adenocarcinoma | 29915(65.2) | 9497(74.4) | 4349(65.3) | 1971(58.2) | 1835(57.5) | 3888(56.3) | 918(47.6) | 7451(67.4) |
Size(cm)—Number(%) | ||||||||
size ≤ 1 cm | 2429(5.3) | 1672(13.1) | 163(2.4) | 61(1.8) | 119(3.7) | 175(2.5) | 27(1.4) | 211(1.9) |
1 < size ≤ 2 cm | 10987(23.9) | 6665(52.2) | 1063(16.0) | 473(14) | 583(18.3) | 949(13.7) | 156(8.1) | 1098(9.9) |
2 < size ≤ 3 cm | 10136(22.1) | 4431(34.7) | 1238(18.6) | 674(19.9) | 455(14.2 | 1344(19.4) | 237(12.3) | 1757(15.9) |
3 < size ≤ 5 cm | 12160(26.5) | – | 4194(63.0) | 916(27.1) | 590(18.5) | 2204(31.9) | 564(29.2) | 3692(33.4) |
5 < size ≤ 7 | 6446(14.0) | – | – | 1260(37.2) | 748(23.4) | 1335(19.3) | 549(28.5) | 2554(23.1) |
size>7 cm | 3746(8.2) | – | – | 699(219) | 904(13.1) | 396(20.5) | 1747(15.8) | |
Site | ||||||||
Upper lobe | 68.79(10.3) | 7691(60.2) | 3970(59.6) | 1857(54.9) | 1955(61.2) | 4280(61.9) | 1258(65.2) | 6705(60.6) |
Middle lobe | 68.36(10.8) | 786(6.2) | 412(6.2) | 178(5.3) | 143(4.5) | 344(5.0) | 88(4.6) | 534(4.8) |
Lower lobe | 69.66(10.4) | 4265(3.3) | 2206(33.1) | 1288(38.1) | 1046(32.7) | 2077(30.1) | 454(23.5) | 3343(30.2) |
Main bronchus | 65.82(11.2) | 27(0.2) | 70(1.1) | 61(1.8) | 50(1.6) | 210(3.0) | 129(6.7) | 477(4.3) |
T stage | ||||||||
T1a | 9970(21.7) | 8310(65.1) | – | 426(12.6) | – | 546(7.9) | 79(4.1) | 545(4.9) |
T1b | 6317(13.8) | 4459(34.9) | – | 451(13.3) | – | 593(8.6) | 89(4.6) | 725(6.6) |
T2a | 11983(26.1) | – | 6658(100) | 1230(36.3) | – | 1711(24.8) | 203(10.5) | 2181(19.7) |
T2b | 3579(7.8) | – | – | 1277(37.7) | 392(12.3) | 700(10.1) | 129(6.7) | 1081(9.8) |
T3 | 7893(17.2) | – | – | – | 2802(87.7) | 1944(28.1) | 238(12.3) | 2910(26.3) |
T4 | 6225(13.6) | – | – | – | – | 1417(20.5) | 1191(61.7) | 3617(32.7) |
N stage | ||||||||
N0 | 27734(60.4) | 12769(100) | 6658 | 1277(37.7) | 2802(87.7) | 1109(1.6) | – | 3119(28.2) |
N1 | 4503(9.8) | – | – | 2107(62.3) | 392(12.3) | 965(14.0) | – | 1039(9.4) |
N2 | 10811(23.6) | – | – | – | – | – | – | 5001(45.2) |
N3 | 2856(6.2) | – | – | – | – | – | 956(49.6) | 1900(17.20) |
