Table 7 Estimates from a multiple linear regression model for age, adjusting for gender, ethnicity (all patients), grade, tumor location and histology type among patients Stages I,II,III disease.

From: Time-to-Progression of NSCLC from Early to Advanced Stages: An Analysis of data from SEER Registry and a Single Institute

Age difference(years): Stages I,II,III

All patients n = 34845

Caucasian n = 28657

African-American n = 3322

Asian n = 2866

Adjusted mean age(years)

 tumor ≤ 1 cm

68.83(68.77~68.9)

69.52(69.48~69.55)

66.04(65.76~66.32)

65.17(65.03~65.31)

 1~2 cm vs. ≤ 1 cm

0.06(−0.01~0.13), p = 0.096

0.02(−0.01~0.07),P = 0.256

−0.005(−0.31~0.30),p = 0.974

0.37(0.2~0.53), p < 0.001

 2~3 cm vs. ≤ 1 cm

0.13(0.05~0.21), p = 0.001

0.1(0.06~0.15), p < 0.001

0.18(−0.15~0.52), p = 0.282

0.69(0.52~0.87), p < 0.001

 3~4 cm vs. ≤ 1 cm

0.34(0.26~0.43), p < 0.001

0.29(0.24~0.35), p < 0.001

0.67(0.30~1.04), p < 0.001

1.13(0.94~1.32), p < 0.001

 4~5 cm vs. ≤ 1 cm

0.59(0.49~0.68), p < 0.001

0.47(0.41~0.53), p < 0.001

0.85(0.47~1.25), p < 0.001

1.28(1.06~1.51), p < 0.001

 5~6 cm vs. ≤ 1 cm

0.73(0.64~0.83), p < 0.001

0.56(0.50~0.62), p < 0.001

1.17(0.75~1.60), p < 0.001

1.69(1.41~1.9), p < 0.001

 6~7 cm vs. ≤ 1 cm

0.85(0.72~0.91), p < 0.001

0.68(0.61~0.75), p < 0.001

1.24(0.81~1.67), p < 0.001

1.76(1.63~2.17), p < 0.001

 7~8 cm vs. ≤ 1 cm

0.76(0.64~0.88), p < 0.001

0.70(0.64~0.75), p < 0.001

1.49(1.03~1.95), p < 0.001

1.81(1.49~2.11), p < 0.001

 >8 cm vs. ≤ 1 cm

0.85(0.64~0.89), p < 0.001

0.79(0.71~0.85), p < 0.001

1.40(0.94~1.86), p < 0.001

1.79(1.41~2.16), p < 0.001

  1. Values given are mean differences in ages by tumor size and stage of disease, with 95%CIs.