Table 2 Microelectrode measurements and repetitive nerve stimulation in R-spondin 2 (Rspo2)−/− mice at embryonic day (E) 18.5.

From: R-spondin 2 promotes acetylcholine receptor clustering at the neuromuscular junction via Lgr5

 

Wild-type

Rspo2−/−

p

MEPP amplitude (mV)

3.38 ± 0.18 (n = 22)

3.86 ± 0.70 (n = 25)

0.04

MEPP frequency (sec−1)

0.65 ± 1.10 (n = 22)

0.07 ± 0.02 (n = 25)

0.01

CMAP area (%)

102.2 ± 1.6 (n = 4)

92.5 ± 0.7 (n = 4)

0.0031

  1. Miniature endplate potentials (MEPPs) were recorded from the left diaphragm of wild-type and Rspo2−/− mice at E18.5. Relative areas of the fifth and first compound muscle action potentials (CMAPs) at the 2-Hz stimulation of the sciatic nerve are indicated. Statistical significance (p) was calculated with the t-test. Mean and standard error of mean (SEM) are indicated.
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