Figure 4: Effect of CTNNB1 polymorphisms on its endogenetic protein expression. | Scientific Reports

Figure 4: Effect of CTNNB1 polymorphisms on its endogenetic protein expression.

From: Pathway Analyses Identify Novel Variants in the WNT Signaling Pathway Associated with Tuberculosis in Chinese Population

Figure 4

Notes: P1-P4: TB patients with mutant genotype of CTNNB1 polymorphisms (rs9859392/rs9870255/rs3864004), i.e. subjects with haplotype [GCA]. P5-P8: TB patients with wild genotype of CTNNB1 polymorphisms, i.e. subjects with haplotype [CGG]. Similarly, H1-H4 and H5-H6 refer to healthy controls with mutant genotype and wild genotype of CTNNB1 polymorphisms, respectively. (A,B) protein levels of β-catenin, phosphorylated β-catenin (p-β-catenin) and β-actin were determined by Western blot in the PBMC of 8 TB patients and 8 healthy controls, respectively. Each bar represents the mean grey value of each group plus standard deviation.

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