Table 4 Random-effects model pooled proportion estimates by major CC epidemiological characteristics.

From: Prevalence and epidemiological characteristics of congenital cataract: a systematic review and meta-analysis

 

Studies

Children

Pooled prevalence (%)

95% CI (%)

Heterogeneity (I2)

95% CI (%)

Laterality

 Bilateral

13

3,646

54.3

[45.9; 62.6]

96.0

[94.5; 97.1]

 Unilateral

13

3,646

45.4

[36.6; 54.1]

96.4

[95.1; 97.4]

Morphology

 Total

6

1,393

31.2

[13.8; 48.7]

97.9

[96.9; 98.6]

 Nuclear

8

2,478

27.2

[16.9; 37.4]

96.7

[95.1; 97.8]

 Posterior subcapsular

4

2,082

26.8

[10.8; 42.8]

98.3

[97.3; 99.0]

 Anterior polar

6

1,481

17.7

[8.04; 27.4]

97.2

[95.7; 98.2]

 Lamellar

4

1,138

10.9

[4.45; 17.3]

75.0

[30.6; 91.0]

 Posterior polar

3

2,023

7.25

[4.49; 10.0]

75.6

[19.4; 92.6]

 Sutural

1

58

5.17

\

\

\

 Mixed

3

1,212

16.8

[7.54; 26.0]

85.5

[58.4; 95.1]

 Others/nonspecific

4

1,186

16.2

[6.60; 25.7]

91.5

[81.5; 96.1]

Comorbidity

 Isolated

5

1,586

62.3

[54.5; 70.2]

85.0

[66.6; 93.2]

 With ocular disorder

6

2,716

22.7

[17.1; 28.2]

87.1

[74.3; 93.5]

 With systemic disorder

6

1,885

17.3

[13.8; 20.7]

63.1

[10.6; 84.8]

Etiology

 Hereditary

9

2,430

22.3

[16.1; 28.4]

91.3

[85.8; 94.7]

 Nonhereditary

5

1,675

11.5

[4.65; 18.3]

92.9

[86.3; 96.3]

 Idiopathic

7

1,994

62.2

[57.2; 67.1]

74.1

[44.7; 87.9]