Figure 2: Behavioral analysis in controls (n = 8) and CP/CPPS rat model (n = 10).

Elevated plus maze (EPM) performance ((A) day 45 and (B) day 60) of controls and CP/CPPS rats. Bars represent time (in %) spent in the open/closed arms, and explorations and entrances (in %) in the open/close arms in 5 min. Open field (OF) performance (C) day 45 and (D) day 60). Bars represent the distance traveled, ambulatory counts (total steps of rats in center zone), and entries into the center zone in the first 5 and 10 min. Y maze performance ((E) day 45 and (F) day 60). Bars represent time spent, latency, and absolute latency staying in the novel arm in 5 min during the 2nd test. (G) Shuttle box passive avoidance (SBPA) performance at day 45 and day 60. Bars represent the latency in the light box on the 2nd test day. *Indicate a significance level of p < 0.05 versus controls. The data are presented as means ± SD.