Figure 2: Gene expression profiles of the 20 primary breast cancers (BC) compared to those of the 41 breast cancer brain metastases (BCBM).
From: Gene Expression Profiling of Breast Cancer Brain Metastasis

Volcano plots show the distribution of the fold changes in gene expression. Genes with absolute fold change ā„2 and adjusted P-value FDRā<ā0.05 are indicated in red (high expression in primary BC compared to BCBM) and blue (low expression in primary BC compared to BCBM). Comparisons were analyzed using Studentās t-test.