Table 1 Baseline characteristics (n = 44).
From: Gene Expression Profiling of Breast Cancer Brain Metastasis
No. | % | |
|---|---|---|
Median age (range), years | ||
At initial diagnosis of BC | 45 (22–64) | |
At initial diagnosis of BCBM | 48 (34–65) | |
Menopausal status (n = 39) | ||
Premenopausal | 31 | 79.5 |
Postmenopausal | 8 | 20.5 |
Histology (n = 42) | ||
Invasive ductal carcinoma | 37 | 88.1 |
Invasive lobular carcinoma | 1 | 2.4 |
Others | 4 | 9.5 |
Grade (n = 32) | ||
Low | 0 | 0 |
Intermediate | 11 | 34.4 |
High | 21 | 65.6 |
T stage at initial diagnosis (n = 34) | ||
T1 | 13 | 38.2 |
T2 | 18 | 52.9 |
T3 | 3 | 8.8 |
T4 | 0 | 0 |
N stage at initial diagnosis (n = 35) | ||
N0 | 11 | 31.4 |
N1 | 12 | 34.3 |
N2 | 6 | 17.1 |
N3 | 6 | 17.1 |
Stage at initial diagnosis (n = 42) | ||
I | 7 | 16.7 |
II | 17 | 40.5 |
III | 13 | 31.0 |
IV | 5 | 11.9 |
Tumor subtype at initial diagnosis (n = 34) | ||
HR+ | 9 | 26.5 |
HER2+* | 11 | 32.3 |
TNBC | 14 | 41.2 |
Distant metastasis prior to the formation of brain lesions | ||
Yes | 19 | 43.2 |
Site of metastasis Lung | 8 | 42.1 |
Bone | 7 | 36.8 |
Liver | 6 | 31.6 |
Pleura | 2 | 10.5 |
Adrenal gland | 1 | 5.3 |
No | 25 | 56.8 |
