Figure 4
From: Azithromycin induces anti-viral effects in cultured bronchial epithelial cells from COPD patients
Effects of azithromycin (AZM) on gene expression of pro-inflammatory cytokines in bronchial epithelial cells from COPD patients.
HBECs from COPD patients were pre-treated with azithromycin for 24 h before infection with 1MOI RV16 and continuous throughout the experiment. Cells were harvested for gene expression analysis 24 h post infection. Gene expression levels of CXCL8 (a) and TNFα (b) were measured by real-time PCR and data is presented as mean ± standard error of the mean (SEM) fold change of RV16 relative to UBC/GAPDH expression. Comparison of different groups was performed by Kruskal-Wallis with Wilcoxon post testing. #p < 0.05, ##p < 0.01 RV16 vs. control; *p < 0.05 AZM vs. RV16. Data was obtained from 5 donors.
