Table 1 Top 20 upregulated genes after ONT.
From: Transcriptome profiling of the rat retina after optic nerve transection
Symbol | Description | RefSeq | Log2 FC | q-value |
|---|---|---|---|---|
Up-regulated | ||||
Ecel1*,†| Endothelin converting enzyme-like 1 | NM_021776 | 5.86 | 1.60E-10 |
Casp4 †| Caspase 4, apoptosis-related cysteine peptidase | NM_053736 | 4.54 | 2.61E-05 |
Stc2 | Stanniocalcin 2 | NM_022230 | 4.07 | 6.39E-14 |
Ifi27l2b | Interferon, alpha-inducible protein 27 like 2B | NM_206846 | 3.76 | 0.00E + 00 |
Tnfrsf12a * | Tumor necrosis factor receptor superfamily, member 12a | NM_181086 | 3.68 | 0.00E + 00 |
Mmp19 | Matrix metallopeptidase 19 | NM_001107159 | 3.63 | 7.89E-03 |
Flnc | Filamin C, gamma | NM_001191862 | 3.35 | 0.00E + 00 |
Gpnmb * | Glycoprotein (transmembrane) nmb | NM_133298 | 3.32 | 0.00E + 00 |
Lgals3 * | Lectin, galactoside-binding, soluble, 3 | NM_031832 | 2.93 | 9.05E-08 |
Krt12 | Keratin 12 | NM_001008761 | 2.89 | 7.62E-06 |
Hspb1 †| Heat shock 27kDa protein 1 | NM_031970 | 2.74 | 4.18E-13 |
Arc | Activity-regulated cytoskeleton-associated protein | NM_019361 | 2.71 | 1.34E-07 |
Hmox1 * | Heme oxygenase 1 | NM_012580 | 2.65 | 5.30E-13 |
Csrnp1 * | Cysteine-serine-rich nuclear protein 1 | NM_001108786 | 2.63 | 8.75E-08 |
Lcn2 | Lipocalin 2 | NM_130741 | 2.52 | 6.80E-12 |
RGD1564664 | Similar to LOC387763 protein | NM_001110055 | 2.43 | 0.00E + 00 |
Csrp3 †| Cysteine and glycine-rich protein 3 | NM_057144 | 2.42 | 1.22E-08 |
Creb5 | cAMP responsive element binding protein 5 | NM_001134621 | 2.39 | 3.93E-02 |
Sox11 * | SRY (sex determining region Y)-box 11 | NM_053349 | 2.36 | 0.00E + 00 |
Chac1*,†| ChaC, cation transport regulator 1 | NM_001173437 | 2.34 | 0.00E + 00 |
