Figure 4: Birefringence imaging of excised breast tumour sample exhibiting patches of low birefringence that are surrounded by regions of higher birefringence. | Scientific Reports

Figure 4: Birefringence imaging of excised breast tumour sample exhibiting patches of low birefringence that are surrounded by regions of higher birefringence.

From: Deep tissue volume imaging of birefringence through fibre-optic needle probes for the delineation of breast tumour

Figure 4

(a) Volume rendering of structural intensity signal (I) and (b) overlay of birefringence and structural signal (I,Δn). (c) Longitudinal cross-section (radial distance from needle versus pullback) of structural intensity signal (I) and (d) corresponding overlay (I,Δn), indicated in (a,b) by dashed lines. Scale bars are 500 μm, assuming a refractive index of tissue of n = 1.36. Colour range indicates birefringence of 0.18 × 10−3–2.2 × 10−3 and regions with a depolarization index <0.3 are displayed in greyscale only. Brightness range is −10–40 dB.

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