Figure 5: Comparison of oblique cross-sections with matching histology of ex-vivo breast tumour samples. | Scientific Reports

Figure 5: Comparison of oblique cross-sections with matching histology of ex-vivo breast tumour samples.

From: Deep tissue volume imaging of birefringence through fibre-optic needle probes for the delineation of breast tumour

Figure 5

(a,d) Structural intensity (I), (b,e) overlay of tissue birefringence and intensity (I,Δn), and (c,f) matching histological section stained with haematoxylin and eosin (H&E). (a–c) are from a wide local excision (lumpectomy) of a 20 mm, grade 1 invasive ductal carcinoma. (d–f) are from a mastectomy of a 20 mm, grade 2 invasive ductal carcinoma. The needle track visible in (c) is due to a needle inserted into the tissue after imaging to guide the collection of histology, and hence does not appear in the OCT images. Scale bar is 1 mm and applies to all panels. Colour range indicates birefringence of 0.18 × 10−3–2.2 × 10−3. Brightness range is −10–40 dB.

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